About Us

Company Mission

 

JOINN Biologics is a Bay Area, California-based CMO company that is committed to the advancement of biopharmaceutics through its premier contract development and manufacturing services for biologics and advanced therapies. JOINN Biologics aims to provide a complete range of services from early custom development to clinical manufacturing for our global clients. We will work closely with our partners and clients to further accelerate the development of high-quality biologics to meet patient’s needs and deliver long-lasting value to biopharmaceutical industry.

 

Management Team

Tao He, PhD

20+ years in pharma (Novartis, Wyeth, and Pfizer). Led multiple biologics programs from preclinical through IND filing.

Jonathan Blackie

25+ years leadership roles (Bayer, Biomarin) in Manufacturing Sciences, Commercial and Clinical Manufacturing Operations, and Global Business Process Integration.

Liang Xia, PhD

15+ years leading new enzyme therapeutics development at clinical and pre-commercialization stages in biopharma (DesigneRx)

Zhiping Yao, PhD

15 years in pharma and biotech for Drug R&D (Merck, Novartis, Harbour Biomed), 20+ years in Protein Production and Analytics

Shumin Yang, PhD

15+ years in Biologic Product and Process Development, especially Upstream Process Development (Boehringer Ingelheim, Catalent)

Wen-Rong Jiang, PhD

20 years in pharma (Roche, Pfizer) for drug R&D, expert in Antibody Drug & Cell Line Development

Vincent Rubino

18+ years in Validation, QA, Commissioning and Qualification for biopharmaceutical manufacturing (Bayer, Biomarin, Sumsung Biologics)

Zelalem Mengesha

20+ years in Engineering for pharmaceutical manufacturing (Bayer)

JOINN GROUP

JOINN Biologics

Pre-Clinical and Clinical Manufacturing

Pre-clinical Evaluation

JOINN Laboratories is the sister company of JOINN Biologics, and has an excellent track record spanning over two decades for non-clinical safety evaluation.

NEWS

JOINN Biologics will present a case study of Developability Assessment at BioProcess International conference, Gene to Market Track, at 10:45am-11:15am on September 10, 2019, at Boston Convention and Exhibition Center (BCEC), Boston, MA
JOINN Biologics was invited to a panel discussion of “Innovative and Collaborative Contract Services to Accelerate Drug Development” at CABS 2019 BioPacific Conference, June 22, 2019, San Mateo, CA
JOINN Biologics presented a poster regarding cell line development at the Cell Line Development and Engineering Conference, June 18-20, 2019, San Francisco, CA
JOINN Biologics presented a poster regarding developability assessment at PEGS the Essential Protein Engineering Summit, April 8-12, 2019, Boston, MA

Careers

Life at JOINN Biologics

JOINN Biologics is a young company filled with energy. Life here is exciting. Here you can fully utilize your own expertise and you can be cross-trained by different departments, for skills from development to manufacturing, and to quality. No matter what field you were in, you can still learn new skills here.

Benefits

JOINN Biologics is an equal opportunity employer offering competitive compensation and benefits, which includes:

  • Health insurance
  • Dental insurance
  • Vision insurance
  • Retirement plan
  • Paid time off
  • Parental leave
 

We are looking for highly motivated and determined individuals to fill the positions below.

To apply, please send your CV and cover letter to career@joinnbio.com

GMP Plant Engineer

Essential Duties and Responsibilities
  • Responsible for the operation and maintenance of all development laboratory and GMP facilities and utilities.
  • Manage the maintenance program for all process and laboratory equipment.
  • Manage facilities systems and maintenance staff, including training, scheduling and review of activities.
  • Responsible for Environmental Health and Safety (EHS) within the scope of responsibilities.
  • Establish SOPs and performance metrics.
  • Prepare, review and execute qualification and validation documents for facilities and clean utilities.
  • Manage changes and deviations, as appropriate.
  • Perform facility risk management and implement corrective plans.
  • Ensure client confidentiality and data integrity.
Experience / Qualification
  • Minimum ten (10) management experience in GMP pharmaceutical facilities operation is required.
  • System owner and process lead for all site sterilization systems (CIP/SIP, Autoclaves, clean steam)
  • Minimum of bachelor’s degree with major in mechanical, electrical or chemical engineering, or equivalent facilities experience is required.
  • Experience in operation of GMP and non-GMP utilities and systems including HVAC, WFI, pure steam, clean dry air, process gases, plant steam, chilled water, waste water, fire protection, electrical power, etc.
  • Knowledgeable about cGMP compliance requirements for pharmaceutical manufacturing facilities.
  • Project management skills and ability to coordinate complex projects under demanding timelines.
  • Excellent communication skills, leadership, and learning ability.
  • Experience with implementation and system ownership of IT systems (ERP, CMMS, MS Project).
  • Lean, 6-sigma and operational excellence background.
  • Self-motivated and organized.
Physical Demands With or Without Accommodation
  • Ability to stand for extended periods of time (approximately 6-8 hours)
  • Ability to repeatedly stoop, kneel, reach, stand, and walk throughout an 8-10 hour shift
  • Ability to lift, push, and/or pull up to 25 kg (55 lbs.)
  • Ability to have clarity and sharpness of vision for activities such as preparing data, transcribing, viewing a computer terminal, and expansive reading
  • Ability to be exposed to considerable noise from machinery
  • Ability to wear PPE as required
  • Work visa sponsorship not available; local candidates preferred.

Job Type: Full-time 

Experience: Management: 5 years (Required) 

Education: Bachelor’s (Preferred) 

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

GMP Manufacturing Associate: Cell Culture

Essential Duties and Responsbilities:
  • Perform unit operations including, but not limit to, inoculum seed train, batching, inoculation of bioreactors, process monitoring, centrifugation, depth filtration and micro filtration; performs and documents work per cGMP; adheres to all regulation and safety standards required by site.
  • Assemble process equipment for CIP/SIP, autoclaving or production, prepare media and transfer into stainless steel or disposable bioreactor.
  • Perform daily analysis of cell culture, maintenance of analytical equipment.
  • Support Installation Qualification/Operational Qualification/Performance Qualification of process equipment.
  • Create or revise SOP and batch records.
  • Maintains work areas to meet cGMP requirement; maintains own training within compliance.
  • Flexible to adapt schedule to meet production demand.
  • May be required to support part cleaning, process assembly preparation, media/buffer preparation.
Experience / Qualification
  • Associate/Bachelor’s degree in science related area or engineering; or biotech certificate with two plus years of experience in a biotech manufacturing environment.
  • Experience in upstream biologics manufacturing is preferred, such as cell cultivation in shaker flasks, stainless steel/disposable bioreactor, cell culture harvest.
  • Ability to work a collaborative environment.
  • Excellent communication skills.

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

GMP Sr. Manufacturing Associate

Essential Duties and Responsbilities:
  •  Independently perform unit operations including, but not limit to, ProA HPLC, SEC, CEX, AEX, UF/DF, Viral Filtration inoculum seed train, batching, inoculation of bioreactors, process monitoring, centrifugation, depth filtration and micro filtration; performs and documents work per cGMP; adheres to all regulation and safety standards required by site
  • Independently assemble process equipment for CIP/SIP, autoclaving or production, prepare media and transfer into stainless steel or disposable bioreactor
  • Perform daily analyses of cell culture, maintenance of analytical equipment
  • Support Installation Qualification/Operational Qualification/Performance Qualification of process equipment
  • Authoring/reviewing SOP and batch records
  • Maintains work areas to meet cGMP requirement; maintains own training within compliance; performs training to peers if needed
  • Flexible to adapt working schedule to meet production demand
  • May be required to support part cleaning, process assembly preparation, media/buffer preparation
Experience / Qualification
  • Associate/Bachelor’s degree in science related area or engineering with two year experience; or biotech certificate with four plus year experience in a biotech manufacturing environment
  • Experience in upstream biologics manufacturing sciences, such as cell cultivation in shaker flasks and bioreactors, cell culture harvest
  • Experience in stainless steel or disposable bioreactor operation and maintenance
  • Ability to work a collaborative environment
  • Excellent communication skills

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

Manager of Manufacturing Operations

Essential Duties and Responsbilities:
The Manager of the Manufacturing Operations department is responsible for the production of clinical/commercial biopharmaceuticals in a multi-product environment. The duties include media/buffer solution preparations, cell culture and bioreactor operation and all protein purification operations. This position provides centralized oversight and administration of Contract Manufacturing Operations.
 
The Manager is accountable for managing the activities of the staff, monitoring the maintenance of production equipment and facilities in the Manufacturing Suite, overseeing complete documentation of all required production activities and ensuring compliance with current Good Manufacturing Practice regulations (cGMP), Standard Operating Procedures (SOPs), product licenses, corporate policies and safety practices.
 
Experience / Qualification
Supervisory and Management:
  • Manage the bulk manufacturing work unit to meet market or inventory demand for two commercial biotechnology products. Monitor inventories and departmental budget. Staff positions as required.
  • Ensure optimal staffing and scheduling of personnel
  • Assure that production equipment and facilities are maintained in proper working condition and in a validated mode by assuring use of Change Control procedures.
  • Lead and roll out Operational Excellence programs targeting department efficiency, production improvements, cost reductions, and deviation reductions.
  • Provide leadership and career development to the manufacturing supervisors.
  • Review and approve all technician, lead and supervisor performance evaluations and promotion recommendations.
  • 50% or more of time is spent in work directly and closely related to carrying out exempt functions.
  • Provide a safe environment for employees. Ensure that monthly Safety and Housekeeping Audits are conducted. Ensure that Departmental Safety Training is performed and documented.
  • Handle Employees’ complaints and disciplining when necessary.
  • Interview, select and train employees.
Scheduling and Training
  • Schedule all manufacturing operations with the facility and regularly communicate the schedule within the manufacturing department and to other groups as necessary.
  • Distribute and delegate work.
  • Supervise the training of operations staff in cell culture and/or purification processes.
  • Technical Leadership:
  • Troubleshoot equipment and process failures.
  • Provide technical expertise to resolve manufacturing issues.
  • Lead process control and optimization programs.
  • Lead process/technology transfer projects, and the final stages of process development.
Documentation
  • Supervise and perform, as needed, the creation and revision of production documents in order to maintain GMP compliance and efficiency. Ensure that all SOPs and batch records are maintained to reflect current manufacturing methods and are in conformance with product licenses.
  • Ensure adequate training of departmental personnel in cGMPs and SOPs. Ensure timely submission and completion of all Manufacturing Investigation Reports and documentation of deviations to minimize production delays.
  • Ensure that all compliance commitments are completed on time and provide documented evidence to support closure of each item according to the established timeline.
  • Generate, review and/or approve all manufacturing operations related documentation, including process validation protocols and variance reports, and the respective follow-up (Document Change Request forms, Engineering and Facility Change Control Request forms, Purchase orders, and Instrumentation Deviation Reports).
  • Work visa sponsorship not available; local candidates preferred.

Job Type: Full-time

Experience: Management: 5 years (Required)

Education: Bachelor’s (Preferred)

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

Business Development Associate / Manager

Essential Duties and Responsbilities:
  • Gain deep understanding about the company’s technology and services
  • Design and execute marketing campaigns to increase brand awareness and generate sales leads
  • Perform market research, identify potential customers, design and executive sales campaigns to reach target customers
  • Attend relevant scientific conferences and trade shows for networking and sales leads generation
  • Manage customer database
  • Follow up with clients to secure sales deals
  • Provide technical consultation to clients as needed
  • Prepare sales proposals to answer customers’ RFPs
  • Negotiate and close deals
  • Bridge between internal teams and external clients to fit sales and project needs
Experience / Qualification
  • Must be self-starter, results-driven, well organized
  • Bachelor’s degree required, in sales/marketing or biotech field
  • Previous business development experience with CRO or CMO preferred; Established network in biopharmaceutical field desired
  • Must be a good listener to understand clients’ needs;
  • Excellent written and oral presentation skills required
  • Must be a good team player, can work effectively with different departments within the company, and with external clients
  • Willing and able to travel up to 50% of time

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

Research Associate /Senior Research Associate in Cell Line Development

Essential Duties and Responsbilities:
  • Cell culture maintenance, cell banking
  • Characterization of cell lines
  • Single cell cloning
  • Characterize and optimize the protein expression
  • Lab and instrument maintenance
  • Generate reliable and high-quality data
  • Accurately document protocols and data, write study reports
  • Summarize and present data
Experience / Qualification
  • Bachelor’s degree or higher in Biological Sciences
  • Laboratory and cell culture experience is preferred
  • Experience in stable cell line generation and recombinant protein expression is highly desired
  • Excellent data analysis and documentation skills
  • Ability to multitask and work collaboratively with other team members

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

Human Resource (HR) Manager

Essential Duties and Responsbilities:
The Human Resource (HR) Manager works closely with the management team to ensure that all Human Resources activities are managed appropriately through clear and concise communication. Additional duties include, but are not limited to, the following:
 
  • Be responsible to drive core HR functions, ensuring to align initiatives, programs, and projects to business drivers and company overall strategy.
  • Take initiatives in the following areas: executive coaching, employee relations, incentive and compensation actions, structure and leveling, employee engagement and culture development, organizational design, change management, employee communications, performance management and people development
  • Help to create a positive working environment and build confidence and skill levels of employees
  • Facilitate recruiting efforts and report current recruitment progress periodically
  • Build relationships with leaders to ensure pro-activity in engaging and retaining talent
  • Proactively identify and solve individual concerns, performance issues, etc., and offer support and assistance as needed
  • Maintain and modify as needed the JOINN Bio Employee Handbook, job descriptions and other HR forms and documents
  • Manage other special projects on an as needed basis
Experience / Qualification
  • Bachelor’s Degree in HR or related field (required)
  • 4+ years in progressively responsible HR roles, preferably with a good track record in a fast-growing startup company (required)
  • Deep familiarity and understanding of all areas of the Human Resources function (required)
  • Experience working with and influencing senior executives (required)
  • Demonstrated success operating as a strategic HR business partner (required)

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

Principal Scientist, Biologics Formulation

Essential Duties and Responsbilities:
The Formulation Principal Scientist will provide technical leadership for the development of pre-clinical and early clinical stage candidates forms following quality by design (QbD) principles for the delivery protein-based therapeutic agents. The successful candidate will be expected to drive programs from inception through pre-clinical manufacture/screening, technology transfer, early cGMP manufacture, working closely with Quality and CMC counterparts as well as any necessary analytical method development, specification development, and assessment of stability data/programs.
 
  • Independently performs and implements formulation strategies
  • Development of inject-able biologics dosage forms following quality by design (QbD) principles
  • Identifies drug product critical quality attributes impacting safety, efficacy, and manufacturing robustness. Provides input to define phase appropriate regulatory specifications
  • Performs screening of buffers, excipients, solubilizers, etc.
  • Preformulation characterization of preclinical and clinical compounds
  • Authoring and review of written documents including development reports, technical memos, etc.
  • Serves as formulation lead in multidisciplinary project teams and/or sub-teams
  • Work effectively in a cross-functional matrix environment, with internal and external customers and proactively communicate with internal and external stakeholders.
Required Experience / Qualifications
  • 10+ years’ industry experience with BS degree in related scientific discipline, or 8+ years’ industry experience with MS degree in related scientific discipline.
  • Will have expert understanding of preformulation and formulation area and uses published literature to extend understanding as well as consulting internal and external experts as needed
  • Highly independent and self-motivated and integrates well within a team
  • Ability to establish and maintain effective working relationships
  • Strong ability to trouble-shoot technical problems
  • Detail oriented, with good organizational skills and project management skills
  • Able to work in a high paced team environment meet deadlines and prioritize work on multiple projects
  • Excellent oral and written communication skills

Job Type: Full-time

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.